Murine Hematopoietic Stem Cells and Multipotent Progenitors Express Truncated Intracellular Form of c-kit Receptor
نویسندگان
چکیده
منابع مشابه
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule.
The proto-oncogene c-kit encodes a transmembrane tyrosine kinase receptor for stem cell factor (SCF). The c-kit/SCF signal is expected to have an important role in hematopoiesis. A monoclonal antibody (ACK-2) against the murine c-kit molecule was prepared. Flow cytometric analysis showed that the bone marrow cells that expressed the c-kit molecule (approximately 5%) were B220(B)-, TER119(erythr...
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ژورنال
عنوان ژورنال: Stem Cells and Development
سال: 2008
ISSN: 1547-3287,1557-8534
DOI: 10.1089/scd.2007.0101