Multisystem disease in post-streptococcal arthritis.

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Multisystem disease in post-streptococcal arthritis.

The case presented is of a patient with migratory polyarthritis and serological evidence of a recent streptococcal infection, consistent with the diagnosis of acute rheumatic fever, who in addition had multisystem disease manifestations. This case supports the concept that the sequelae of streptococcal infection can encompass a broader clinical spectrum than is suggested by the Jones criteria f...

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Group A Streptococcus is a common bacterium that induces tonsillitis, pharyngitis, and pyoderma, and, furthermore, its metabolic products cause scarlatina. It is suggested that the molecular mimicry and cross reactivity between human tissues and the micro-organism are associated with immunogenic pathogenesis of well known poststreptococcal manifestations: acute rheumatic fever and acute glomeru...

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Post-streptococcal reactive arthritis: where are we now

A 35-year-old man presented with polyarthritis and constitutional symptoms, and a recent history of multiple tick bites and skin rash on trekking holiday. He did not respond to oral doxycycline and cephalexine for presumed Lyme's disease. Further investigation confirmed strongly positive streptococcal serology. There was absence of clinical or echocardiography evidence of heart involvement and ...

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Differentiation of post streptococcal reactive arthritis from acute rheumatic fever

OBJECTIVE To perform a retrospective study comparing clinical and laboratory aspects of patients with acute rheumatic fever (ARF) and patients with post-streptococcal reactive arthritis (PSRA), to discern whether these are 2 separate entities or varying clinical manifestations of the same disease. STUDY DESIGN We located the records of 68 patients with ARF and 159 patients with PSRA, whose di...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1991

ISSN: 0003-4967

DOI: 10.1136/ard.50.5.328