Multi?Responsive Jammed Micro?Gels Ink: Toward Control over the Resolution and the Stability of 3D Printed Scaffolds

3D printing of hydrogels usually relies on a combination fine-tuned material chemistry and polymer chain architecture to obtain an ink with adequate yield-stress flow, shear-thinning, self-healing behavior. Recent approaches in hydrogel design include introduction reversible covalent or supramolecular bonds jamming microparticles into granular hydrogel. However, the dimensional stability such systems is typically afforded by post-printing cross-linking step that impedes further on-demand degradation scaffolds. Here, jammed micro-gels made thermosensitive poly(N-isopropylacrylamide) incorporating terpyridine ligand linkers are proposed as printable cured iron (II) cations for long-term stabilization. The uncross-linked exhibits rheological characteristics materials, meaning yield-stress, shear-thinning fast recovery. Upon curing, (II)-bis-terpyridine coordination complexes between neighboring formed. sufficiently strong long-lived maintain scaffold integrity during manual handling immersion liquid medium over two months. thermosensitivity endows printed construct cyclable temperature-induced resolution enhancement, while provides asset disintegration on-demand. micro-gel scaffolds biocompatible, revealing potential biomedical applications 4D bioprinting.