Multiplexing experiments in NMR and multi-nuclear MRI
نویسندگان
چکیده
• A review on multinuclear and homonuclear multi-FID detection methods in liquids solids. These techniques allow experiment multiplexing, dramatically increasing information content, sensitivity speed. New supersequences enable elucidation of molecular structure from a single measurement. Pulse schemes with complete resonance assignment protein Applications include use multiple microcoils routed to receivers MRI. Multiplexing NMR experiments by direct free induction decays (FIDs) offers dramatic increase the spectral content often yields significant improvement per unit time. Experiments have been designed both acquisition, advent commercial spectrometers opens up new possibilities for recording spectra different nuclear species parallel. Here we provide an extensive overview such techniques, applications liquid- solid-state as well hyperpolarized samples. brief MRI is also provided, stimulate cross fertilization ideas between two areas research (NMR MRI). It shown how design that small molecules Likewise, biomolecular allows proteins. Probes RF alternative way throughput modern systems, effectively reducing cost analysis at same Solid-state benefited immensely parallel sequential variety multi-dimensional pulse schemes. We are confident will become essential component future methodologies, measurements.
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Department of Radiology, Vanderbilt University Institute of Imaging Science, Nashville, TN 37232; Department of Chemistry and Biochemistry, Southern Illinois University, Carbondale, IL 62901; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235; Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham NG7 2RD, United Kingdom; Department of ...
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ژورنال
عنوان ژورنال: Progress in Nuclear Magnetic Resonance Spectroscopy
سال: 2021
ISSN: ['0079-6565', '1873-3301']
DOI: https://doi.org/10.1016/j.pnmrs.2021.03.001