Multiple transcripts encoding lamprey gonadotropin-releasing hormone-I precursors
نویسندگان
چکیده
منابع مشابه
Multiple transcripts encoding lamprey gonadotropin-releasing hormone-I precursors.
The cDNA encoding lamprey prepro-gonadotropin releasing hormone-I (lamprey GnRH-I) has been isolated and sequenced in an agnathan, the sea lamprey, Petromyzon marinus. The lamprey GnRH-I precursor is the first identified in an ancient lineage of vertebrates and has the same overall tripartite structure as other vertebrate GnRH precursors. The amino acid sequence of lamprey GnRH-I and the proces...
متن کاملGonadotropin-releasing hormone neurons in the preoptic-hypothalamic region of the rat contain lamprey gonadotropin-releasing hormone III, mammalian luteinizing hormone-releasing hormone, or both peptides.
This study utilized a newly developed antiserum, specific for lamprey gonadotropin-releasing hormone III (l-GnRH-III), to determine the following: in which regions of the rat hypothalamus the neuronal perikarya producing l-GnRH-III are localized; and whether this peptide, known to selectively induce follicle-stimulating hormone release, is coexpressed in neurons containing mammalian luteinizing...
متن کاملImmunization of pigs against chicken gonadotropin-releasing hormone-II and lamprey gonadotropin-releasing hormone-III: effects on gonadotropin secretion and testicular function.
The objective of this experiment was to evaluate the effects of active immunization against 2 GnRH isoforms on gonadotropin secretion and testicular function in pigs. Synthetic chicken (c) GnRH-II and lamprey (l) GnRH-III peptides, with the common pGlu-His-Trp-Ser sequence at the N-terminal omitted, were conjugated to BSA. Forty-eight male piglets were randomly assigned to 1 of 4 treatments. Pi...
متن کاملGonadotropin-releasing hormone containing neurons and olfactory fibers during development: from lamprey to mammals.
Gonadotropin releasing-hormone (GnRH) regulates the hypothalamo-pituitary-gonadal axis in all vertebrates. The vast majority of GnRH neurons are thought to be derived from progenitor cells in medial olfactory placodes. Several antibodies and lectins that recognize cell surface carbohydrates have been useful for delineating the migratory pathway from the olfactory placodes and vomeronasal organ,...
متن کاملCharacterization and localization of gonadotropin-releasing hormone receptors in the adult female sea lamprey, Petromyzon marinus.
Quantitative in vitro autoradiography was used to characterize and localize putative GnRH receptors in the anterior pituitary of the adult female sea lamprey, Petromyzon marinus. Pituitaries were sectioned at 20 microns and incubated for 3 h at 4 C with DAla6,Pro9 NEt mammalian GnRH as both the labeled and unlabeled ligand. Scatchard analysis revealed two classes of high affinity binding sites ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2000
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme.0.0240365