Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients
نویسندگان
چکیده
منابع مشابه
Ocular surface squamous neoplasia in HIV-infected patients: current perspectives
Ocular surface squamous neoplasia (OSSN) refers to a spectrum of conjunctival and corneal epithelial tumors including dysplasia, carcinoma in situ, and invasive carcinoma. In this article, we discuss the current perspectives of OSSN associated with HIV infection, focusing mainly on the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of these tumors in patients w...
متن کاملOcular surface squamous neoplasia among HIV-infected patients in Botswana.
BACKGROUND Ocular surface squamous neoplasia (OSSN) is a group of ocular tumours that has been rising in incidence among HIV-infected individuals in sub-Saharan Africa. Surgical excision is the mainstay of treatment for OSSN in this region. METHODS This retrospective cohort study examined the clinical characteristics and treatment modalities used for 468 patients with OSSN from a large tertia...
متن کاملOcular Surface Squamous Neoplasia
The ocular surface is composed of the conjunctiva and the cornea. The conjunctiva is a mucous membrane which covers the globe and inner part of the eyelids. The morphology of conjunctival epithelial cells are nonkeratinized stratified epithelia which vary from cuboidal over the tarsus, to columnar in the fornices, to squamous epithelia on the globe. Goblet cells account for up to 10% of the bas...
متن کاملCytokine and Chemokine Expression Profiles in HIV-1 Infected Patients With Ocular Surface Squamous Neoplasia From Botswana
Purpose: Ocular surface squamous neoplasia (OSSN) rate has increased in incidence with the HIV pandemic in Africa. Multiple factors including cellular and environmental can affect the pathogenesis of OSSN in HIVinfected patients. We will investigate anti-inflammatory cytokines, proinflammatory cytokines, and growth factor expression in sera and tissue samples of OSSN and pterygia for the potent...
متن کاملOcular surface squamous neoplasia in HIV-positive and HIV-negative patients and response to 5-fluorouracil in Angola
BACKGROUND Ocular surface squamous neoplasia (OSSN) is becoming increasingly prevalent and aggressive in Sub-Saharan Africa. It is a phenomenon linked with human immunodeficiency virus (HIV) infection, although association rates in Angola are currently unknown. A topical treatment that is effective in HIV-positive and HIV-negative individuals may be preferable to surgery in some contexts. We ai...
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ژورنال
عنوان ژورنال: Infectious Agents and Cancer
سال: 2010
ISSN: 1750-9378
DOI: 10.1186/1750-9378-5-6