منابع مشابه
Multiple Drug Hypersensitivity.
Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs. The initial symptoms are mostly severe exanthems or drug rash with eosinophilia and systemic symptoms (DRESS). Subsequent symptoms due to another drug often appear in the following weeks, o...
متن کاملMultiple drug hypersensitivity--proof of multiple drug hypersensitivity by patch and lymphocyte transformation tests.
BACKGROUND Multiple drug hypersensitivity (MDH) was first described in 1989 by Sullivan et al. as drug allergies to two or more chemically different drugs. So far, the diagnosis of MDH was associated almost exclusively with antibiotics and was defined based on history alone. AIMS OF THE STUDY The objective of this study was to prove MDH by two independent tests, namely patch (PT) and lymphocy...
متن کاملDrug Hypersensitivity
The in vitro diagnosis of allergic reactions to drugs is of particular interest to clinicians, as neither the clinical history nor the in vivo tests are fully conclusive. In addition, these tests may often be associated with risk, as occurs with the drug provocation test. Various different in vitro tests are available for the evaluation of drug hypersensitivity depending on the immunological me...
متن کاملMinocycline-induced drug hypersensitivity syndrome followed by multiple autoimmune sequelae.
BACKGROUND Drug hypersensitivity syndrome (DHS) is a severe, multisystem adverse drug reaction that may occur following the use of numerous medications, including anticonvulsants, sulfonamides, and minocycline hydrochloride. Long-term autoimmune sequelae of DHS have been reported, including hypothyroidism. OBSERVATIONS A 15-year-old female adolescent developed DHS 4 weeks after starting minoc...
متن کاملThe multiple faces of nonsteroidal antiinflammatory drug hypersensitivity.
Based on the clinical picture and triggering drugs, allergic and pseudoallergic adverse reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) can be classified in four patterns : respiratory, cutaneous, mixed and systemic. This categorization is useful for the purpose of describing patient populations included in studies about NSAID adverse reactions as well as for the routine management o...
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ژورنال
عنوان ژورنال: International Archives of Allergy and Immunology
سال: 2017
ISSN: 1018-2438,1423-0097
DOI: 10.1159/000458725