Multiple Dimensions of Schizotypy in First Degree Biological Relatives of Schizophrenia Patients

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Multiple dimensions of schizotypy in first degree biological relatives of schizophrenia patients.

Considerable research has been devoted to identifying individuals predisposed to schizophrenia, with much of the effort devoted to identifying the personality characteristics of the biological relatives of schizophrenia patients. Although resource-consuming interviews have yielded promising results, investigators have long sought self-report measures that index genetic risk for schizophrenia. T...

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Neurocognitive correlates of schizotypy in first degree relatives of schizophrenia patients.

We examined neurocognitive correlates of three dimensions of schizotypy in 63 healthy first degree relatives of schizophrenia patients. Neurocognitive measures of attention, verbal memory, and prefrontal functioning were combined with self-report and interview measures of schizotypy. State-psychopathology (anxiety and depression) was a strong predictor for positive schizotypy (PS) and negative ...

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Schizotypal Traits among Patients with Schizophrenia, Their Non-Psychotic First-Degree Relatives, and Normal Controls

Evidence has suggested that risk for schizophrenia is likely to occur in non-psychotic first-degree relatives of patients with schizophrenia. On the other hand, schizotypal personality disorder is genetically related to schizophrenia. The aim of this study was to compare schizotypal traits (i.e., positive schizotypy, negative schizotypy, cognitive disorganization, and impulsive nonconformity) a...

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Social Cognition in Schizophrenia Patients and Their First-Degree Relatives.

INTRODUCTION Social cognition is a person's ability to configure the designs of relationships between themselves and others and to use these designs to guide social behaviors in a flexible manner. The models that are the most studied and describe social cognition are the theory of mind (ToM) and emotion recognition. This study was aimed to detect ToM and emotion recognition disorders in schizop...

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Saccadic disinhibition in patients with acute and remitted schizophrenia and their first-degree biological relatives.

OBJECTIVE Performance on measures of saccadic inhibition and control was investigated in a large family study of schizophrenia to evaluate the utility of using antisaccade task performance as an endophenotypic marker of genetic liability for schizophrenia. METHOD Ninety-five patients with acute schizophrenia and 116 of their first-degree biological relatives, 13 schizophrenia patients whose i...

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ژورنال

عنوان ژورنال: Schizophrenia Bulletin

سال: 2004

ISSN: 0586-7614,1745-1701

DOI: 10.1093/oxfordjournals.schbul.a007081