Multiple cutaneous lipomatous neurofibromas
نویسندگان
چکیده
منابع مشابه
Carbon Dioxide Laser Treatment of Cutaneous Neurofibromas
INTRODUCTION Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder, with multisystem involvement, including cutaneous manifestations of hyperpigmentation and neurofibromas. Multiple cutaneous lesions are often disfiguring and lead to emotional distress and social isolation. Treatment of NF1 is predominantly surgical but alternative treatments should be considered for patients with la...
متن کاملMultiple radiation-induced neurofibromas.
A 49-year-old woman had received radiotherapy at the axillar, clavicular, and left laterocervical regions for Hodgkin lymphoma. Fifteen years later, she reported progressive loss of strength and sensation in her left arm. The patient had no stigma of neurofibromatosis or any other genetic mutation. Cervical MRI showed neurofibromas (figure 1). A cervical laminectomy was performed and multiple n...
متن کاملHypertrophic scars after therapy with CO2 laser for treatment of multiple cutaneous neurofibromas.
BACKGROUND CO2 laser surgery is a treatment modality for cutaneous neurofibromas. OBJECTIVE Hypertrophic and atrophic scars can result from treatment with CO2 laser surgery. We present a case of cutaneous neurofibromatosis that developed hypertrophic scars postoperatively. METHODS Continuous wave CO2 laser surgery therapy was applied to the patient. RESULTS Hypertrophic scars developed 2 ...
متن کاملClinico-pathological and biomolecular findings in Italian patients with multiple cutaneous neurofibromas
BACKGROUND Neurofibroma occurs as isolated or multiple lesions frequently associated with neurofibromatosis type 1 (NF1), a common autosomal dominant disorder affecting 1 in 3500 individuals. It is caused by mutations in the NF1 gene, which comprises 60 exons and is located on chromosome 17q11.2. NF1 is a fully penetrant gene exhibiting a mutation rate some 10-fold higher compared with most oth...
متن کاملMast cell numbers in melanocytic naevi and cutaneous neurofibromas.
This study aimed to determine the diagnostic utility of mast cell densities in distinguishing neurotised ("neural") melanocytic naevi from neurofibromas. Three groups of lesions were studied: neurofibromas, neural naevi, and naevi showing no neural change (control naevi). A Giemsa stain was used to demonstrate mast cells. The median mast cell density in the neurotised naevus group was significa...
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ژورنال
عنوان ژورنال: Dermatology Online Journal
سال: 2016
ISSN: 1087-2108
DOI: 10.5070/d3222030100