Multiple Chronic Conditions and Heart Failure

Multiple biomarkers for risk prediction in chronic heart failure.

BACKGROUND Prior studies have suggested using a panel of biomarkers that measure diverse biological processes as a prognostic tool in chronic heart failure. Whether this approach improves risk prediction beyond clinical evaluation is unknown. METHODS AND RESULTS In a multicenter cohort of 1513 chronic systolic heart failure patients, we measured a contemporary biomarker panel consisting of hi...

Delivering Chronic Heart Failure Telemanagement via Multiple Interactive Platforms

Existing telemonitoring systems provide limited support in implementing personalized treatment plans. We developed a Home Automated Telemanagement (HAT) system for patients with congestive heart failure (CHF) to provide support in following individualized treatment plans as well as to monitor symptoms, weight changes, and quality of life, while educating the patient on their disease. The system...

Advanced Chronic Heart Failure and Heart Transplantation

Selenium and Chronic Heart Failure

To the Editor: We read with interest the article by Inoko et al about selenium deficiency,1 but we do not agree with the interpretation of the data. Selenium deficiency was identified as a factor in the etiology of heart failure syndromes in areas of very low selenium intakes, such as China, where an endemic selenium-responsive cardiomyopathy is called Keshan disease.2 Similar cases of cardiomy...

Anemia and Chronic Heart Failure

Anemia is a common comorbidity in patients with heart failure and is associated with worse long-term outcomes. Although the cause of anemia in heart failure is unclear, the weight of evidence suggests that renal dysfunction, along with neurohormonal and proinflammatory cytokine activation in heart failure, favors the development of anemia of chronic disease, with defective iron utilization, ina...