Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management

The development of general anesthesia techniques and anesthetic substances has opened new horizons for the expansion improvement surgical techniques. Nevertheless, more complex procedures have brought a higher complexity longer duration anesthesia, which led to series adverse events such as hemodynamic instability, under- or overdosage drugs, an increased number post-anesthetic events. In order adapt according particularities each patient, multimodal monitoring these patients is highly recommended. Classically, consists analysis vital functions gas exchange. Multimodal refers concomitant degree hypnosis nociceptive-antinociceptive balance. By titrating drugs parameters, clinical benefits can be obtained, stabilization, reduction awakening times, postoperative complications. Another important aspect impact on status inflammation redox minimizing inflammatory oxidative impact, faster recovery achieved that increases patient safety. purpose this literature review present most modern discuss technique.