Multinomial-Sampling Models for Random Genetic Drift
نویسندگان
چکیده
منابع مشابه
Multinomial-sampling models for random genetic drift.
Three different derivations of models with multinomial sampling of genotypes in a finite population are presented. The three derivations correspond to the operation of random drift through population regulation, conditioning on the total number of progeny, and culling, respectively. Generations are discrete and nonoverlapping; the diploid population mates at random. Each derivation applies to a...
متن کاملMultinomial logit random effects models
This article presents a general approach for logit random effects modelling of clustered ordinal and nominal responses. We review multinomial logit random effects models in a unified form as multivariate generalized linear mixed models. Maximum likelihood estimation utilizes adaptive Gauss–Hermite quadrature within a quasi-Newton maximization algorithm. For cases in which this is computationall...
متن کاملUrn Models, Replicator Processes, and Random Genetic Drift
To understand the relative importance of natural selection and random genetic drift in finite but growing populations, the asymptotic behavior of a class of generalized Polya urns is studied using the method of ordinary differential equation (ODE). Of particular interest is the replicator process: two balls (individuals) are chosen from an urn (the population) at random with replacement and bal...
متن کاملRandom Genetic Drift & Gene Fixation
Random Genetic Drift is one of the evolutionary forces that effects the distribution of alleles and changes their frequencies in populations. The main idea behind this theory is that genetic changes can happen randomly. This can be explained through the Bottleneck effect. There are two main factors that have an influence on genetic drift, the first one is the Effective Population Size Ne , whic...
متن کاملRandom genetic drift and gamete frequency.
An analytic expression of conditional expectation of transient gamete frequency, given that one of the two loci remains polymorphic, is obtained in terms of the diffusion process by calculating the moments of the distribution. Using this expression, a model where linkage disequilibrium is introduced by a single mutation is considered. The conditional expectation of the gamete frequency given th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetics
سال: 1997
ISSN: 1943-2631
DOI: 10.1093/genetics/145.2.485