Multimodality Treatment of Malignant Glioma
نویسندگان
چکیده
منابع مشابه
Biology and Treatment of Malignant Glioma
Gliomas are rare compared to cancers of the breast, lung, or colon, but few malignancies are more devastating. While no therapeutic breakthroughs have occurred, the treatment of glioma is improving. Surgical care is improving. Magnetic resonance imaging and intraoperative mapping studies are leading to safer, more complete resections. With scan-guided stereotactic biopsy, unresectable tumors ca...
متن کاملTemozolomide and treatment of malignant glioma.
Malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) occur more frequently than other types of primary central nervous system tumors, having a combined incidence of 5-8/100,000 population. Even with aggressive treatment using surgery, radiation, and chemotherapy, median reported survival is less than 1 year. Temozolomide, a new drug, has shown promise in treating malignant gli...
متن کاملBiology and treatment of malignant glioma.
A large number of oncogenes have been identified as aberrant in gliomas, but only the erbB oncogene (gene encoding the epidermal growth factor receptor [EGFR]) is amplified in an appreciable number. The loss or mutation of tumor-suppressor genes located on different autosomes may be associated with progression of malignant gliomas. The p53 tumor-suppressor gene (located on chromosome 17) is fre...
متن کاملBiology and Treatment of Malignant Glioma
Gliomas are rare compared to cancers of the breast, lung, or colon, but few malignancies are more devastating. While no therapeutic breakthroughs have occurred, the treatment of glioma is improving. Surgical care is improving. Magnetic resonance imaging and intraoperative mapping studies are leading to safer, more complete resections. With scan-guided stereotactic biopsy, unresectable tumors ca...
متن کاملTreatment of malignant glioma using hyperthermia
Thirty pathologically diagnosed patients with grade III-IV primary or recurrent malignant glioma (tumor diameter 3-7 cm) were randomly divided into two groups. The control group underwent conventional radiotherapy and chemotherapy. In the hyperthermia group, primary cases received hyperthermia treatment, and patients with recurrent tumors were treated with hyperthermia in com-bination with radi...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 1984
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.24.19