Multimodal MRI Features of Medulloblastoma with Extensive Nodularity and Activated Sonic Hedgehog: A Case Report

: Medulloblastoma with extensive nodularity (MBEN) is a rare histological subtype of medulloblastomas in very young children. It characterized by an aggressive grape-like appearance and favorable outcomes. Herein, we report the case nine-month-old patient MBEN, associated activated sonic hedgehog (SHH), multimodal magnetic resonance imaging (MRI) features. Conventional MRI findings indicated dense homogeneous enhancement large unusual gyriform mass cerebellar vermis both hemispheres. The showed restricted diffusion on diffusion-weighted images, low concentrations taurine MR spectroscopy, relatively cerebral blood volume dynamic susceptibility contrast (DSC) perfusion image. underwent partial tumor resection, chemotherapy, autologous stem cell transplantation. After treatment, lesion rapidly regressed serial follow-up without recurrence.