Multidrug resistance in Gram-negative bacteria that produce extended-spectrum β-lactamases (ESBLs)

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منابع مشابه

[Extended-spectrum beta-lactamases (ESBLs) producing bacteria].

TEM- or SHV-type extended-spectrum beta-lactamases(ESBLs) are of clinical concern in Europe and the United States, whereas bacterial strains producing such types of ESBLs had not been reported in Japan for many years. Toho-1, a different type class A ESBL, has been reported in 1995, in which any prototypical enzyme has not been identified so far. At present Toho-1 is the major ESBL in Japan, ho...

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Bacteria Producing Extended Spectrum β-lactamases (ESBLs) in Hospitalized Patients: Prevalence, Antimicrobial Resistance Pattern and its Main Determinants

Background and Objective: There is a growing concern regarding the lack of new antibiotics, especially for multidrug-resistant bacteria that produce Extended Spectrum β-Lactamases (ESBLs). The present study aims to assess the prevalence of bacteria producing ESBLs, their antimicrobial resistance pattern, and its main determinants among hospitalized patients.Method...

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Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria

CTX-M enzymes, the plasmid-mediated cefotaximases, constitute a rapidly growing family of extended-spectrum β-lactamases (ESBLs) with significant clinical impact. CTX-Ms are found in at least 26 bacterial species, particularly in Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis. At least 109 members in CTX-M family are identified and can be divided into seven clusters based on thei...

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The Importance of Extended-Spectrum β-lactamases in Gram-Negative Enteric Bacilli and the Phenotypic Methods of detection

The production of β-lactamase enzymes is the main mechanism of resistance to β-lactam antibiotics in gramnegative bacilli. Therefore, it is important to identify the β-lactamases-producing bacteria for the treatment of caused infections. This article aimed to review the recent literature and guidelines regarding phenotypic detection of β-lactamases in common gram-negative bacilli in clinical sa...

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detection of extended-spectrum β-lactamases (esbls) in escherichia coli

background escherichia coli (e. coli) species are able to produce extended-spectrum β-lactamases (esbls) that cause high resistance to the beta-lactam antibiotics. therefore, determining the antibiotic susceptibility patterns in resistant organisms is necessary for suitable therapeutic approaches. patients and methods totally, 260 clinical isolates of e. coli were collected from hospitals in te...

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ژورنال

عنوان ژورنال: Clinical Microbiology and Infection

سال: 2005

ISSN: 1198-743X

DOI: 10.1111/j.1469-0691.2005.01160.x