Multi-Bead-and-Spring Model to Interpret Protein Detachment Studied by AFM Force Spectroscopy
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چکیده
منابع مشابه
Single-protein Afm-based Force Spectroscopy Nyu-csmr
The recently developed single molecule force spectroscopy enables the detailed study of the mechanisms of protein unfolding and refolding under a stretching force. It has revealed many signatures of complexity of the underlying energy landscape that were previously overlooked in bulk experiments. For example, the broad distribution of unfolding times of the protein ubiquitin has been suggestive...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2002
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(02)75202-8