Mucosal secretory IgA and secretory piece in adult coeliac disease
نویسندگان
چکیده
منابع مشابه
Mucosal secretory IgA and secretory piece in adult coeliac disease.
Immunofluorescence studies with specific antisera to secretory IgA (11S IgA) and secretory piece were carried out on the jejunal mucosa of nine patients with adult coeliac disease (treated and untreated). The results were compared with those obtained in four normal patients and in four patients with local and systemic IgA (7S) deficiency. 11S IgA and secretory piece were localized to the upper ...
متن کاملProtection against Mucosal Infections by Secretory IgA
In the past decade, several model systems have been developed to study the details of the production of secretory IgA by the mucosal surface. Until recently, most attention in vaccine research has been directed toward establishing a vigorous systemic (predominantly IgG) humoral immune response to the infectious agent. With the recognition, however, that secretory IgA is overwhelmingly the predo...
متن کاملMulti-Faceted Functions of Secretory IgA at Mucosal Surfaces
Secretory IgA (SIgA) plays an important role in the protection and homeostatic regulation of intestinal, respiratory, and urogenital mucosal epithelia separating the outside environment from the inside of the body. This primary function of SIgA is referred to as immune exclusion, a process that limits the access of numerous microorganisms and mucosal antigens to these thin and vulnerable mucosa...
متن کاملRecombinant secretory IgA for immune intervention against mucosal pathogens.
Mucosal epithelia of the human body, including the lining of the digestive, respiratory and urogenital tracts, comprises a vast surface permanently exposed to attack by exogenous pathogens. Protection of mucosal surfaces against colonization and possible invasion by pathogenic microorganisms is provided by a combination of constitutive non-specific substances such as mucus, lysozyme, lactoferri...
متن کاملComparison of Salivary Secretory IgA in Caries-free Children and Children with Severe Early Childhood Caries
Background & Aims: Sever early childhood caries (SECC) is a multifactor common disease that unfortunately there have been a lot of unknown points about it. This study was performed to compare the levels of total S-IgA in children with and without SECC. Methods: In this cross-sectional study 44 children aged 6-24 months were divided into two groups of with SECC (n=20) and without SECC (n=24). Th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 1973
ISSN: 0017-5749
DOI: 10.1136/gut.14.10.778