منابع مشابه
Correlation between QRS Complex Changes and Cardiac Iron Overload in Beta Thalassemia Major Patients Using T2*MRI
Background and purpose: Cardiac magnetic resonance imaging (MRI) is a costly method to assess cardiac iron overload. The presence of fragmented QRS (fQRS) indicates changes due to iron overload in cardiac tissue. The aim of this study was to evaluate the correlation between fQRS and cardiac iron overload using cardiac MRI in patients with β-thalassemia major (β-TM). Materials and methods: This...
متن کاملEvaluation of the relationship between hepatic and cardiac iron overload with MRI T2* and carotid intima media thickness with Doppler ultrasound in beta thalassemia major patients
Background: Iron overload is caused early progression of atherosclerosis in beta thalassemia patients due to regular repeated blood transfusion. MRI T2* is a gold standard non-invasive method for detecting hepatic and cardiac iron overload. The aim of this study was the comparison of carotid intima media thickness (CIMT) in the patients and healthy control groups with Doppler ultrasound for ear...
متن کاملQuantification of severe liver iron overload using MRI offset echoes
Magnetic resonance imaging (MRI) has become the clinical standard to estimate liver iron overload. The most commonly used method is to measure the transversal relaxation time, T2*, from a multi gradient recalled echo sequence (MGRE). While this technique is reliable in low to moderate liver iron concentrations (LIC), it will be inaccurate when it is severe. We report a case with severe liver he...
متن کاملMultislice Multiecho T2* MRI assessment of regional pancreatic iron overload and correlation with cardiac biventricular function and myocardial iron overload in thalassemia major patients
Introduction: Thalassemia major (TM) patients require lifelong iron load monitoring to assess the effectiveness of chelation therapies. Multiecho T2* MRI is a well established technique for heart and liver iron overload assessment [1]. There are few reports on the use of MRI to study iron deposits in the pancreas. The aims of this study were to describe the T2* values of the pancreas in patient...
متن کاملTreatment of cardiac iron overload in thalassemia major.
The inexorable tissue iron accumulation in thalas-semia major is well documented and is fatal unless chelation therapy is given to remove the iron from the tissues. Desferal thus revolutionized the treatment of iron overload in thalassemia and dramatically improved survival. Desferal has been widely available now for over two decades and initially it was thought that life expectancy might be op...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2012
ISSN: 1053-1807
DOI: 10.1002/jmri.23628