MP833ASSESSMENT OF THE VALUE OF URINARY KIDNEY INJURY MOLECULE-1 (UKIM -1) AS AN EARLY PREDICTOR OF ACUTE KIDNEY INJURY (AKI) IN FULL TERM ASPHYXIATED NEONATES
نویسندگان
چکیده
منابع مشابه
Diagnostic Value of Urinary Kidney Injury Molecule 1 for Acute Kidney Injury: A Meta-Analysis
BACKGROUND Urinary Kidney Injury Molecule 1 (KIM-1) is a proximal tubular injury biomarker for early detection of acute kidney injury (AKI), with variable performance characteristics depending on clinical and population settings. METHODS Meta-analysis was performed to assess the diagnostic value of urinary KIM-1 in AKI. Relevant studies were searched from MEDLINE, EMBASE, Pubmed, Elsevier Sci...
متن کاملUrinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury.
Sensitive and specific biomarkers are needed to detect early kidney injury. The objective of the present work was to develop a sensitive quantitative urinary test to identify renal injury in the rodent to facilitate early assessment of pathophysiological influences and drug toxicity. Two mouse monoclonal antibodies were made against the purified ectodomain of kidney injury molecule-1 (Kim-1), a...
متن کاملNetrin-1 and kidney injury. II. Netrin-1 is an early biomarker of acute kidney injury.
Acute kidney injury is an important complication in hospitalized patients often diagnosed late and associated with high mortality and morbidity. Although biomarkers for nephrotoxicity are available, they often lack sensitivity and specificity for detecting tubular injury. Netrin-1 is a laminin-like molecule highly expressed in many organs including kidney. To determine the value of netrin-1 as ...
متن کاملUrinary strem-1 is an early outcome predictor for sepsis and sepsis-induced acute kidney injury
Methods Thirty critically ill patients (pts.) with sepsis (57.6 ± 7.5 y, 18 males) and a subset of 10 controls (45.6 ± 3.5 y, 7 males) were included in this study. Urinary sTREM-1 and C-reactive protein (CRP) serum levels were measured on admission, day 3 and 7, respectively. SOFA score was estimated at baseline and daily until discharge, death or up to 28 days. ICU length of stay, need for mec...
متن کاملUrinary kidney injury molecule-1 (Kim-1): a sensitive quantitative biomarker for early detection of kidney tubular injury
Sensitive and specific biomarkers are needed to detect early kidney injury. The objective of the present work was to develop a sensitive quantitative urinary test to identify renal injury in the rodent to facilitate early assessment of pathophysiological influence and drug toxicity. Two mouse monoclonal antibodies were made against the purified ectodomain of kidney injury molecule-1 (Kim-1) and...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2017
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfx183.mp833