Mouse mammary tumor virus-like gene sequences are present in lung patient specimens
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چکیده
منابع مشابه
Mouse Mammary Tumor Virus–like Sequences in Human Breast Cancer
Authors' A Sciences, F of Medicin 3Austrianov Forensic S Australia; 5 Area Health 6Douglas H Note: Supp Online (http In this artic human bre malignanci Correspon and Biomo Sydney, N Fax: 61-2-9
متن کاملMouse mammary tumor virus-like gene sequences in breast tumors of Australian and Vietnamese women.
PURPOSE There is considerable evidence that the presence of mouse mammary tumor virus (MMTV)-like gene sequences in human breast cancer is highly associated with human breast carcinoma. Previous studies have found MMTV-like gene sequences in 38% of breast cancer tissue from United States women. The prevalence of these sequences in Australian and Vietnamese women has never been reported. EXPER...
متن کاملExpression of mouse mammary tumor virus-like env gene sequences in human breast cancer.
We have reported previously (Wang et al, Cancer Res., 55: 5173-5179, 1995) the presence of a 660-bp sequence that is 90-98% homologous to the env gene of mouse mammary tumor virus in 38% of 314 unselected breast cancer samples, in some breast cancer cell lines, and in 1.8% of the 107 normal breast specimens from reduction mammoplasties. In this communication, we have investigated whether the 66...
متن کاملA new common integration site, Int7, for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin-like sequences.
A novel common integration site for the mouse mammary tumor virus (MMTV) was identified (designated Int7) in five independently arising mouse mammary tumors. The insertion sites all cluster within a 1-kb region that is 2 to 3 kb 5' of the transcription initiation site of a gene, 2610028F08RIK, whose gene product contains furin-like and thrombospondin-like sequences. Expression of Int7 is normal...
متن کاملMouse mammary tumor virus-like env sequences in human breast cancer.
Mouse mammary tumor virus (MMTV) has long been known as a causal agent of breast cancer in mice. To date, varied MMTV-like envelope gene (env) sequences have been identified in up to 74% of human breast cancers. However, the role and origin of these MMTV-like sequences in human breast cancer remain uncertain. Our study was initiated to study the integration of MMTV-like env sequences in human b...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2011
ISSN: 1743-422X
DOI: 10.1186/1743-422x-8-451