Motor neurone disease and exposure to lead

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Motor neurone disease and exposure to lead.

Disease of the lower motor neurone is a recognized hazard of lead toxicity, but the importance of contact with lead in the causation of motor neurone disease has not previously been ascertained. In 74 cases of motor neurone disease, 15% had a history of extensive exposure to lead, compared with 5·4% of a control group. The five year survival rate of these patients was 54%, compared with 16% in ...

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Motor neurone disease is a relatively common condition with a gross prevalence rate of about 4 per 100,000 (Kurland, 1957). It is fairly uniformly distributed throughout the world, with the exception of the Chamorro population of Guam and Rota in the Mariana Islands and Chamorro emigrants in California. In this ethnic group the prevalence is about 420 per 100,000 (Kurland, 1957) and familial ex...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1970

ISSN: 0022-3050

DOI: 10.1136/jnnp.33.6.877