Motor Dysfunction as a Prodrome of Parkinson’s Disease
نویسندگان
چکیده
منابع مشابه
Premotor Symptoms as Predictors of Outcome in Parkinsons Disease: A Case-Control Study
BACKGROUND To evaluate the association between the premotor symptoms and the prognosis of PD. METHODS A total of 1213 patients who were diagnosed of PD from January 2001 to December 2008 were selected from the Taiwan's National Health Insurance Research Database. Patients were traced back to determine the presence of premotor symptoms, including rapid eye movement sleep behavior disorder (RBD...
متن کاملStriatal Dopamine Depletion Patterns and Early Non-Motor Burden in Parkinsons Disease
BACKGROUND The mechanism underlying non-motor symptoms in Parkinson's disease has not yet been elucidated. In this study, we hypothesized that Parkinson patients with more non-motor symptoms have a different pattern of striatal dopamine depletion, particularly in areas other than the sensorimotor striatum, compared to those with fewer non-motor symptoms. METHODS We conducted a prospective sur...
متن کاملErectile dysfunction as a sentinel marker of endothelial dysfunction disease.
INTRODUCTION Vascular disease is the major underlying cause of erectile dysfunction (ED). Endothelial dysfunction acts as a marker of "peripheral vascular disease" that occurs prior to clinical vascular disease. ED is the first clinical manifestation of endothelial disease due to the small size of the penile artery. Brachial flow-mediated vasodilation (FMD) is one of the accurate tests for eval...
متن کاملManual Therapy Choices: A General Approach to Parkinsons Disease
In treating dysfunction, it is normal for most therapists to use a variety of modalities and methods including myofascial release, muscle-energy techniques, positional-release techniques and many more. The assumption must be that different tools achieve different effects, and the ones we choose reflect our perception as to the needs of the individual and/or of the tissues involved. Sledgehammer...
متن کاملAlterations in striato-thalamo-pallidal intrinsic functional connectivity as a prodrome of Parkinson's disease
Although the diagnosis of Parkinson's disease (PD) remains anchored around the cardinal motor symptoms of bradykinesia, rest tremor, rigidity and postural instability, it is becoming increasingly clear that the clinical phase of the disease is preceded by a long period of neurodegeneration, which is not readily evident in terms of motor dysfunction. The neurobiological mechanisms that underpin ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Parkinson's Disease
سال: 2020
ISSN: 1877-7171,1877-718X
DOI: 10.3233/jpd-191851