Motoo Kimura (1924-1994)

Motoo Kimura (1924-1994).

Motoo Kimura and James Crow on the Infinitely Many Alleles Model.

Kimura and Crow’s 1964 article is justly regarded as one of the foundational articles of evolutionary molecular genetics. It is based on what they called the “infinite alleles” model (now called the “infinitely many alleles” model). This model was motivated by the recognition that a gene is a sequence of perhaps several thousand nucleotides, implying that an astronomically large number of allel...

Postpartum psychosis: two cohorts compared, 1875-1924 and 1994-2005.

BACKGROUND There has been a long-standing debate as to whether postpartum psychoses are distinct from other psychoses. While the outcomes of postpartum psychosis are in general thought to be good, the disorder is linked to a high rate of suicide. METHOD We have utilized a database of 3872 admissions to the North Wales Asylum during the period 1875-1924 to extract data on the prevalence, cours...

Mortality in schizophrenia and related psychoses: data from two cohorts, 1875–1924 and 1994–2010

OBJECTIVE To investigate death rates in schizophrenia and related psychoses. DESIGN Data from two epidemiologically complete cohorts of patients presenting for the first time to mental health services in North Wales for whom there are at least 1, and up to 10-year follow-up data have been used to calculate survival rates and standardised death rates for schizophrenia and related psychoses. ...

CT of Kimura disease.

Kimura is credited with first describing a condition-eosinophilic granuloma of the soft tissue-that subsequently has been given his name. Since then, more than 500 cases have been reported in review series, mainly in the Chinese and Japanese literature [1]. The disease occurs only in Orientals, and more than 80% of these patients are male. Presentation may occur over a wide age range, but it is...