Motility Contrast Imaging for Drug Screening Applications
نویسندگان
چکیده
منابع مشابه
Applications of gold nanoparticles for medical imaging
Background & Aim: Molecular imaging enables us to non-invasively visualize tissue microstructures and lesion characterization, allowing accurate diagnosis of diseases at early stages. A successful molecular imaging requires a nontoxic contrast agent with high sensitivity. Nowadays, a wide range of nanoparticles have been developed as contrast agents for medical imaging modalities. Here, we revi...
متن کاملActivity based probes for proteases: applications to biomarker discovery, molecular imaging and drug screening.
Recent advances in global genomic and proteomic methods have lead to a greater understanding of how genes and proteins function in complex networks within a cell. One of the major limitations in these methodologies is their inability to provide information on the dynamic, post-translational regulation of enzymatic proteins. In particular proteases are often synthesized as inactive zymogens that...
متن کاملSimulation of a Neutron Detector for Real Time Imaging Applications
Monte Carlo Method is used to simulate a double layer gadolinium-amorphous silicon thermal neutron detector. The detector fabricated in pixel array configuration has various applications including neutron imaging. According to the simulation results, a detector consisting of a gadolinium (Gd) film with thickness of 2-4 ~m, sandwiched properly with two layers of sufficiently thick (-30 ?µm) hydr...
متن کامل“Contrast agents for optoacoustic imaging: design and biomedical applications”
Nanoparticles and molecular chromophores with strong optical absorption in the near-infrared spectral range can be used as contrast agents for optoacoustic (photoacoustic) imaging, thereby significantly enhancing sensitivity and enabling new applications of this novel and rapidly growing biomedical imaging technology.
متن کاملNew Platforms For Drug Screening And Toxicology: Necessity Or Need?
The liver is the largest internal organ in the human body that is responsible for more than 500 vital functions, including biosynthesis of major plasma proteins, immunity against infectious pathogens, balancing energy metabolism and xenobiotics biotransformation (1). One of the main functions of the liver is an important role in drug metabolism (2). Since developing new drug compounds into mark...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Optical Society of Korea
سال: 2015
ISSN: 1226-4776
DOI: 10.3807/josk.2015.19.4.382