منابع مشابه
Creating mosaics in Drosophila.
The ability to create mosaic animals allows the phenotypic analysis of patches of groups of genetically different cells that develop in a wild type environment. In Drosophila, a variety of techniques have been developed over the years to generate mosaics, and in this chapter, I review the techniques that our laboratory has developed. These include the "Dominant Female Sterile" technique which a...
متن کاملCoincidence of Crossing over in DROSOPHILA MELANOGASTER (AMPELOPHILA).
PAGE INTRODUCTION .................................................................. I35 Coincidence of widely separated regions. , 138 Coincidence in the second chromosome. 146 Coincidence in the third chromosome. 148 Coincidence in other forms 148 The mechanism of crossing over 148 Triple crossing over .: .. I49 Maximum and minimum coincidence. I53 The distance between the breaking points in ...
متن کاملGerm cell selection in genetic mosaics in Drosophila melanogaster.
Heritable mutations in the germ line lead to genetically heterogeneous, or mosaic, gonads. Many of the genes used in germ-line development also play roles in somatic development [Saffman, E. E. & Lasko, P. (1999) Cell. Mol. Life Sci. 55, 1141-1163]. Mutations in these genes may have cellular phenotypes throughout germ-line development leading to their differential elimination or survival, as ha...
متن کاملSerotonin synthesis and distribution in Drosophila dopa decarboxylase genetic mosaics.
In Drosophila, the enzyme dopa decarboxylase (DDC) catalyzes the last step in the biosynthesis of serotonin (5HT) and dopamine. In the present study, the distribution of DDC and one of its biosynthetic products (5HT) was determined in CNSs that were genetic mosaics, composed of neurons that have DDC activity and neurons that lack DDC activity. Phenotypic mosaicism, that is, immunoreactive (IR) ...
متن کاملThe Formation of Dumpy Vortices in Mosaics of Drosophila Melanogaster.
NTERMEDIATE patterns in development have been termed “prepatterns” I by STERN (1954a,b). STERN hypothesized that the determinations of some cells depend on the particular environments of their positions in intermediate patterns and that some genes may act to alter these patterns. A genetically based change in the prepattern could thus indirectly affect the final pattern of differentiated cells....
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ژورنال
عنوان ژورنال: Genetics
سال: 1916
ISSN: 1943-2631
DOI: 10.1093/genetics/1.6.581