Morphometric study of rat jejunum enterocyte after L-Arginine and L-NAME prescription
نویسندگان
چکیده
Background: Nitric Oxide (NO) is a very important signaling molecule which acts as regulator of many physiological processes in tissues including epithelial cell gastrointestinal tract. In this study we investigated the effects L-Arginine NO progenitor and L-NAME inhibitor on number height Jejunum female rats.
منابع مشابه
Effects of L-arginine and L-NAME on ischemia-reperfusion in rat liver.
PURPOSE To evaluated the effects of L-arginine (a NO donor) and L-NAME (Nw-nitro-L-arginine methyl ester - a NOS inhibitor) on ischemia-reperfusion in rat livers. METHODS One hundred fifty two male Wistar rats were divided into four groups: control (simulated surgery); hepatic IR; pretreatment with L-arginine plus hepatic IR; and L-NAME plus hepatic IR. The hepatocellular damage was evaluated...
متن کاملThe effect of L-arginine and L-NAME on intravenous self-administration of morphine in rats
The involvement of nitric oxide (NO) in the reinforcing properties of opiate reward was studied by examining the effect of a NO precursor (L-arginine) and a NO synthase inhibitor (L-NAME) on the rate of intravenous self-administration of morphine. This experiment was investigated in male albino Sprague Dawley rats (300 ± 50 g). At doses of 5 and 10 mg/kg (i.p.), L-arginine decreased morphine ...
متن کاملEffects of L-Arginine and L-NAME on Duodenal Histologic Parameters in Female Wistar Rats
Introduction: Nitric oxide (NO), as a free radical, involves in several physiologic functions in GI tract such as nerve impulse transmission and vascular tonicity regulation. Nitric oxide synthase (NOS) is the enzyme for the production of NO from L-Arginine which in turn inhibits by L-NGNitroarginine Methyl Ester (L-NAME). In the current work, we aimed to evaluate morphometric analysis of...
متن کاملL-Arginine, nitric oxide, and intestinal secretion: studies in rat jejunum in vivo.
BACKGROUND L-Arginine has been shown to induce fluid secretion in human jejunum. Nitric oxide, a derivative of L-arginine is thought to have an important role as an intestinal secretagogue. AIM To determine the effect of L-arginine and the nitric oxide synthase inhibitor, nitro L-arginine methyl ester (L-NAME), on fluid and electrolyte movement in rat jejunum. METHODS A 25 cm segment of rat...
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ژورنال
عنوان ژورنال: ???? ???? ?????
سال: 2022
ISSN: ['1023-5922', '2008-3386']
DOI: https://doi.org/10.52547/iau.32.2.132