Morphological Changes of Motor Units in Duchenne's Muscular Dystrophy
نویسندگان
چکیده
منابع مشابه
Cardiorespiratory changes in progressive muscular dystrophy.
Incipient cardiac failure was detected in 56 per cent of cases of pseudohypertrophic muscular dystrophy, 50per cent oflimb girdle type ofmyopathies, and2 of the 3 cases with 'unclassifled' variety. 'Myopathic pattern' in the electrocardiogram was seen in 82 per cent of the cases of pseudohypertrophic muscular dystrophy who showed abnormal haemodynamics. This suggests that this pattern is due to...
متن کاملMonitoring changes and predicting loss of ambulation in Duchenne muscular dystrophy with the Motor Function Measure.
AIM To assess changes in motor function in patients with Duchenne muscular dystrophy using the Motor Function Measure (MFM). METHOD Three studies were performed. Two studies included only physiotherapy-treated patients, with 13 patients (males mean age 11y 7mo, SD 1y 10mo, range 8-14y) in the 3-month study and 41 patients (males mean age 14y 1mo, SD 5y 5mo, range 6-32y) in the 1-year study. A...
متن کاملP164: Adeno-Associated Viral Vectors in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (BMD) is an inherited X-link disease. The incidence of this muscle-wasting disease is 1:5000 male live births. Mutation in the gene coding for dystrophin is the main cause of BMD. Most cases of this disease succumb to respiratory and cardiac failure in 3rd to 4th decades. The slow progression of BMD and recent achievement of gene therapies make it as an appropriate c...
متن کاملFurther motor unit studies in Duchenne muscular dystrophy.
Numbers of functioning motor units have been estimated in 124 muscles of boys with Duchenne dystrophy; some of the patients were studied on several occasions. In the distal muscles examined (extensor digitorum brevis, thenar, and hypothenar muscles) the losses of units were probably present at birth and did not decrease with age. In contrast, the numbers of units and of excitable muscle fibres ...
متن کاملMotor assessment in patients with Duchenne muscular dystrophy.
OBJECTIVE Evaluate muscle force and motor function in patients with Duchenne muscular dystrophy (DMD) in a period of six months. METHOD Twenty children and adolescents with diagnosis of DMD were evaluated trough: measurement of the strength of the flexors and extensors of the shoulder, elbow, wrist, knee and ankle through the Medical Research Council (MRC), and application of the Motor Functi...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 1977
ISSN: 0003-9942
DOI: 10.1001/archneur.1977.00500190030004