More Harm than Good: Why Dictionaries Using Orthographic Transcription Instead of the IPA Should Be Handled with Care

Why I think antidepressants cause more harm than good.

DJN has received grants and personal fees from Lundbeck and GSK; and personal fees from Lilly, BMS, Otsuka, Servier, and Pfi zer. GMG has received grants and personal fees from Servier and Lundbeck; personal fees from Teva, Otsuka, Takeda, Eli Lilly, Merck, GSK, and AstraZeneca; and grants from P1vital. DJN and GMG have a small number of stocks in P1vital, a CNS experimental medicine research c...

Ultrasound: more harm than good?

PSA in screening for prostate cancer: more good than harm or more harm than good?

The aim of screening for prostate cancer is to detect malignancy at an early and potentially treatable stage, thereby increasing the chance of cure. Although serum PSA has been used as a screening test for prostate cancer for over 20 years, the practice is controversial. As a screening test for prostate cancer, PSA lacks sensitivity and specificity for early disease. Furthermore, screening may ...

Why Good Quality Care Needs Philosophy More Than Compassion; Comment on “Why and How Is Compassion Necessary to Provide Good Quality Healthcare?”

Although Marianna Fotaki’s Editorial is helpful and challenging by looking at both the professional and institutional requirements for reinstalling compassion in order to aim for good quality healthcare, the causes that hinder this development remain unexamined. In this commentary, 3 causes are discussed; the boundary between the moral and the political; Neoliberalism; and the underdevelopment ...

Guidelines have done more harm than good.

Practice guidelines have proliferated in medicine but their impact on actual practice and outcomes is difficult, if not impossible, to quantify. Though guidelines are based largely on observational data and expert opinion, it is widely believed that adherence to them leads to improved outcomes. Data to support this belief simply does not exist. If guidelines are universally ignored, their impac...