More about quantitative trait locus mapping with diallel designs
نویسندگان
چکیده
منابع مشابه
Advances in Quantitative Trait Locus Mapping
The mapping of loci underlying variation in quantitative traits is proving to be a powerful tool in genetic studies of animals and other organisms. Quantitative trait locus (QTL) mapping in crosses between genetically diverse lines has shown the presence of many QTL, as similarly have studies within livestock populations. Although much remains to be done with this type of analysis, higher resol...
متن کاملCombined Expression Trait Correlations and Expression Quantitative Trait Locus Mapping
Coordinated regulation of gene expression levels across a series of experimental conditions provides valuable information about the functions of correlated transcripts. The consideration of gene expression correlation over a time or tissue dimension has proved valuable in predicting gene function. Here, we consider correlations over a genetic dimension. In addition to identifying coregulated ge...
متن کاملBayesian mapping of quantitative trait loci under complicated mating designs.
Quantitative trait loci (QTL) are easily studied in a biallelic system. Such a system requires the cross of two inbred lines presumably fixed for alternative alleles of the QTL. However, development of inbred lines can be time consuming and cost ineffective for species with long generation intervals and severe inbreeding depression. In addition, restriction of the investigation to a biallelic s...
متن کاملThe X chromosome in quantitative trait locus mapping.
The X chromosome requires special treatment in the mapping of quantitative trait loci (QTL). However, most QTL mapping methods, and most computer programs for QTL mapping, have focused exclusively on autosomal loci. We describe a method for appropriate treatment of the X chromosome for QTL mapping in experimental crosses. We address the important issue of formulating the null hypothesis of no l...
متن کاملQuantitative trait locus mapping can benefit from segregation distortion.
Segregation distortion is a phenomenon that has been observed in many experimental systems. How segregation distortion among markers arises and its impact on mapping studies are the focus of this work. Segregation distortion of markers can be considered to arise from segregation distortion loci (SDL). I develop a theory of segregation distortion and show that the presence of only a few SDL can ...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 2000
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672399004358