Monocyte nonspecific esterase: purification and subunit structure
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چکیده
منابع مشابه
Monocyte nonspecific esterase: purification and subunit structure.
Monocyte nonspecific esterase has been purified from cultured cells of the acute myeloid leukemia cell line, ML-1. The purified enzyme shows the characteristic properties of the monocyte neutral serine carboxyl esterase, with high sensitivity to organophosphorus inhibitors and sodium fluoride inhibitor. The enzyme is a membrane protein which in the native state exists as a monomer of a mol wt o...
متن کاملMonocyte Nonspecific Esterase: Purification and Subunit Structure
Monocyte nonspecific esterase has been purified from cultured cells of the acute myeloid leukemia cell line. ML-l. The purified enzyme shows the characteristic properties of the monocyte neutral serine carboxyI esterase, with high sensitivity to organophosphorus inhibitors and sodium fluoride inhibitor. The enzyme is a membrane protein which in the native state exists as a monomer of a mol wt o...
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AIMS To examine the possibility that monocyte esterase deficiency (MED) could be caused by exposure to organophosphates. METHODS Pseudocholinesterase, paraoxonase and arylesterase activities were measured in the serum and acetylcholinesterase activity was measured in the red cells of a group of monocyte esterase deficient subjects and compared with the enzyme activities of a control group of ...
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Organop iosphat, insecticides, such as Vapona, Naled, and Rabon, are highly potent inhibitors of an enzyme found in human monocytes. The enzyme, a specific monocyte esterase, could be inhibited by Vapona in blood samples via airborne contamination at levels easily achieved from commercial slow-release insecticide strips. Fifty percent inhibition (150)-as measured on the Hemalog D ( Technicon Co...
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The O-linked oligosaccharides (O-glycans) in mammalian glycoproteins are classified according to their core structures. Among the most common is the core 1 disaccharide structure consisting of Gal 133GalNAc 13Ser/ Thr, which is also the precursor for many extended Oglycan structures. The key enzyme for biosynthesis of core 1 O-glycan from the precursor GalNAc-Ser/Thr is UDP-Gal:GalNAc-Ser/Thr 3...
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ژورنال
عنوان ژورنال: Blood
سال: 1986
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v68.2.479.479