Monoaminergic Markers Across the Cognitive Spectrum of Lewy Body Disease

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Neurochemical markers do not correlate with cognitive decline in the Lewy body variant of Alzheimer disease.

BACKGROUND Reductions in neocortical synapses and cholinergic function occur in patients with Alzheimer disease (AD) and in patients with the Lewy body variant of AD (LBV). The relation between these losses and cognitive decline has been reported frequently in patients with AD but remains unclear for patients with LBV. OBJECTIVES To investigate the relation between clinical markers of disease...

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ژورنال

عنوان ژورنال: Journal of Parkinson's Disease

سال: 2018

ISSN: 1877-7171,1877-718X

DOI: 10.3233/jpd-171228