Monoamine Interactions in Narcolepsy and Hypersomnia: A Preliminary Report
نویسندگان
چکیده
منابع مشابه
Causes of Hypersomnia – Narcolepsy
Volitional sleep deprivation and obstructive sleep apnea are the most common causes of hypersomnia. The remaining causes are primarily due to p r imary cen t r a l ne rvous sys t em abnormalities, the most common of which is narcolepsy, a primary disorder of the neural control of wakefulness and sleep.
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BACKGROUND A close association between narcolepsy and the Human Leukocyte Antigen (HLA)-DQB1*0602 allele suggests the involvement of the immune system, or possibly an autoimmune process. We investigated serum IgG levels in narcolepsy. METHODOLOGY/PRINCIPAL FINDINGS We measured the serum total IgG levels in 159 Japanese narcolepsy-cataplexy patients positive for the HLA-DQB1*0602 allele, 28 id...
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The discovery that hypocretins are involved in narcolepsy, a disorder associated with excessive daytime sleepiness, cataplexy, and unusually rapid transitions to rapid eye movement sleep, opens a new field of investigation in the area of disorders of sleep and activation. Hypocretin-1 (hcrt-1) and hypocretin-2 (hcrt-2) (also called orexin-A and orexin-B) are newly discovered neuropeptides proce...
متن کاملA comparison of idiopathic hypersomnia and narcolepsy-cataplexy using self report measures and sleep diary data.
Eighteen patients with idiopathic hypersomnia (IH) were compared with 50 patients with the narcoleptic syndrome of cataplexy and daytime sleepiness (NLS) using self report questionnaires and a diary of sleep/wake patterns. The IH group reported more consolidated nocturnal sleep, a lower propensity to nap, greater refreshment after naps, and a greater improvement in excessive daytime sleepiness ...
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ژورنال
عنوان ژورنال: Sleep
سال: 1986
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleep/9.1.246