Monitoring of chimerism after allogeneic hematopoietic stem cell transplantation
نویسندگان
چکیده
Allogeneic hematopoietic stem cells transplantation is one of the effective methods treating patients with diseases blood system. Establishment complete (100%) donor chimerism among main indicators successful in such cases. Monitoring makes it possible both to assess graft acceptance, and also potentially predict risk developing primary/secondary failure, relapse, graft-versus-host disease. The purpose this review summarize concepts associated after allogeneic cell transplantation; consideration need study various populations, as well relationship between development immunological complications.
منابع مشابه
Relationship between Molecular Chimerism and Graft Versus Host Disease after Allogenic Hematopoietic Stem Cell Transplantation
Background: Bone marrow transplantation (BMT) is considered as a curative therapy for a broad range of diseases. However, complications such as relapse and graft versus host disease (GVHD) may be observed following BMT. Chimerism analysis serves as a reliable indicator of transplant outcome. Complete chimerism refers to the complete replacement of hematopoietic system by donor cells, while mixe...
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ژورنال
عنوان ژورنال: ????????????????
سال: 2022
ISSN: ['2713-2951']
DOI: https://doi.org/10.23873/2074-0506-2022-14-4-488-499