Molecular similarity-based predictions of the Tox21 screening outcome
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چکیده
منابع مشابه
Molecular similarity-based predictions of the Tox21 screening outcome
To assess the toxicity of new chemicals and drugs, regulatory agencies require in vivo testing for many toxic endpoints, resulting in millions of animal experiments conducted each year. However, following the Replace, Reduce, Refine (3R) principle, the development and optimization of alternative methods, in particular in silico methods, has been put into focus in the recent years. It is general...
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ژورنال
عنوان ژورنال: Frontiers in Environmental Science
سال: 2015
ISSN: 2296-665X
DOI: 10.3389/fenvs.2015.00054