منابع مشابه
Molecular Dynamics Computer Simulations of Multidrug RND Efflux Pumps
Over-expression of multidrug efflux pumps of the Resistance Nodulation Division (RND) protein super family counts among the main causes for microbial resistance against pharmaceuticals. Understanding the molecular basis of this process is one of the major challenges of modern biomedical research, involving a broad range of experimental and computational techniques. Here we review the current st...
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The realization of artificial molecular motors capable of converting energy into mechanical work is a fascinating challenge of nanotechnology and requires reactive systems that can operate away from chemical equilibrium. This article describes the design and construction of a simple, supramolecular ensemble in which light irradiation causes the directional transit of a macrocycle along a nonsym...
متن کاملDNA Helicases: New Breeds of Translocating Motors and Molecular Pumps
Jezewska, 1995). The conformation of the hexamer is DNA helicases play essential roles in key biological proaltered by ATP and DNA binding, and two distinct allocesses such as the replication, repair, recombination, steric states (exhibiting 3-fold or 6-fold symmetry) have and transcription of DNA. Their presence and imporbeen observed (Yu et al.,1996). The C3 structure appears tance in DNA met...
متن کاملInsulin pumps.
I nsulin pump therapy—continuous subcutaneous insulin infusion (CSII)—was developed in the UK in the 1970s. Rapid technological developments changed the initial pumps from the size of a house brick, charged by mains electricity to an acceptable dimension, battery driven. We described the use of pumps in young people with type 1 diabetes (T1D) in the UK in Archives of Disease in Childhood in the...
متن کاملComparing pumps.
Comparative evolutionary studies have greatly aided our understanding of how the heart develops. Two recent articles from Benoit Bruneau’s laboratory reveal the power of the so-called evo-devo approach and provide yet further details of development, both of the heart itself and of the cells that build it. Thanks to our many and varied primitive cousins, developmental biologists are gaining a go...
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ژورنال
عنوان ژورنال: SHINKU
سال: 1960
ISSN: 0559-8516,1880-9413
DOI: 10.3131/jvsj.3.300