Molecular Phenotypes of Kidney Graft Rejection
نویسندگان
چکیده
منابع مشابه
Molecular Phenotypes of Kidney Graft Rejection
In the last decade, gene expression studies of kidney transplants provided an opportunity to better understand the development and regulation of kidney graft rejection. This review outlines the progress in the definition of biomarkers of rejection and, above all, concentrates on studies of the molecular phenotype of rejection. This phenotype, rather than morphological characterization, may be c...
متن کاملMolecular Phenotypes of Kidney Graft Rejection
In the last decade, gene expression studies of kidney transplants provided an opportunity to better understand the development and regulation of kidney graft rejection. This review outlines the progress in the definition of biomarkers of rejection and, above all, concentrates on studies of the molecular phenotype of rejection. This phenotype, rather than morphological characterization, may be c...
متن کاملMolecular phenotypes of kidney graft rejection.
In the last decade, gene expression studies of kidney transplants provided an opportunity to better understand the development and regulation of kidney graft rejection. This review outlines the progress in the definition of biomarkers of rejection and, above all, concentrates on studies of the molecular phenotype of rejection. This phenotype, rather than morphological characterization, may be c...
متن کاملMolecular phenotypes of acute rejection predict kidney graft prognosis.
Earlier detection of antibody-mediated rejection of kidney allografts may improve graft outcomes. Profiling of gene expression holds promise for the diagnosis and prognosis of antibody-mediated rejection. Here, we identified 730 patients who received kidney transplants during 2002-2005, including 21 patients (2.9%) who experienced early acute antibody-mediated rejection. We also identified a ma...
متن کاملAssessing rejection-related disease in kidney transplant biopsies based on archetypal analysis of molecular phenotypes.
Conventional histologic diagnosis of rejection in kidney transplants has limited repeatability due to its inherent requirement for subjective assessment of lesions, in a rule-based system that does not acknowledge diagnostic uncertainty. Molecular phenotyping affords opportunities for increased precision and improved disease classification to address the limitations of conventional histologic d...
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ژورنال
عنوان ژورنال: Kidney and Blood Pressure Research
سال: 2011
ISSN: 1423-0143,1420-4096
DOI: 10.1159/000326895