Molecular mimicry: histone H3 and mycobacterial protein epitopes.
نویسندگان
چکیده
منابع مشابه
Molecular mimicry: histone H3 and mycobacterial protein epitopes.
A 15-kDa protein detected initially in amyloidotic ileum from a transgenic mouse and subsequently in control (nontransgenic) ileum by various polyclonal rabbit antiserums applied to electroblots of extracts derived from these tissues was identified by partial sequence analysis as histone H3. Antiserums were made against immunogens unrelated to the histone, but they recognized calf thymus histon...
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Multiple posttranslational modifications (PTMs) of histone proteins including site-specific phosphorylation of serine and threonine residues govern the accessibility of chromatin. According to the histone code theory, PTMs recruit regulatory proteins or block their access to chromatin. Here, we report a general strategy for simultaneous analysis of both of these effects based on a SILAC MS sche...
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The translation of genetic messages into proteins on ribosomes is catalyzed by a number of proteins that bind transiently to the ribosome [1,2]. These are the initiation, elongation and release (termination) factors. Several of these factors are GTP-hydrolyzing (G) proteins, which undergo a conformation transition between an active state with bound GTP and an inactive state with bound GDP. In b...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1995
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.92.6.2150