منابع مشابه
Induction, acceleration or prevention of autoimmunity by molecular mimicry.
The hypothesis that cross-reactivity between microbial and self determinants recognized by the adaptive immune system could induce autoimmune diseases is very intriguing. However, definite proof in humans is very difficult to achieve and evidence is frequently circumstantial. Therefore, animal models are instrumental for understanding, how and when mimicry could be involved in the pathogenesis ...
متن کاملMolecular basis of antigen mimicry by an anti-idiotope
Molecular basis of antigen mimicry by an antiidiotope. Title Molecular basis of antigen mimicry by an anti-idiotope. Publication Type Journal Article Year of Publication 1995 Authors Fields, BA, Goldbaum, FA, Ysern, X, Poljak, RJ, Mariuzza, RA Journal Nature Volume 374 Issue 6524 Pagination 739-42 Date Published 1995 Apr 20 ISSN 0028-0836
متن کاملInduction of cardiac autoimmunity in Chagas heart disease: a case for molecular mimicry.
Up to 18 million of individuals are infected by the protozoan parasite Trypanosoma cruzi in Latin America, one third of whom will develop chronic Chagas disease cardiomyopathy (CCC) up to 30 years after infection. Cardiomyocyte destruction is associated with a T cell-rich inflammatory infiltrate and fibrosis. The presence of such lesions in the relative scarcity of parasites in the heart, sugge...
متن کاملAntigenic mimicry, clonal selection and autoimmunity.
The triggering of autoimmunity by infection or immunization is often blamed on antigenic mimicry. But the concept of antigen mimicry impinges on our understanding of adaptive immunity in general, and not only on autoimmunity. Here are some thoughts about the consequences of immune mimicry.
متن کاملMolecular mimicry
EditoriAL EditoriAL Over the course of evolution, microorganisms have developed innovative survival strategies to thrive in their hosts. 1 The human body is home to many species of bacteria, viruses, fungi, and other invertebrate parasites. Some of these organisms that live and thrive in humans are com-mensals and are harmless. They may be also beneficial to the host as they provide certain nut...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2000
ISSN: 0970-1915,0974-0422
DOI: 10.1007/bf02867547