Molecular karyotyping of single sperm with nuclear vacuoles identifies more chromosomal abnormalities in patients with testiculopathy than fertile controls: implications for ICSI
نویسندگان
چکیده
منابع مشابه
Incidence of sperm chromosomal abnormalities in a risk population: relationship with sperm quality and ICSI outcome.
BACKGROUND An increased incidence of chromosome abnormalities has been reported in sperm samples of many infertile men by fluorescence in-situ hybridization (FISH). METHODS Sperm aneuploidy and diploidy rates for chromosomes 13, 18, 21, X and Y were evaluated in 63 patients with normal karyotypes using dual and triple-colour FISH techniques. Indications for sperm FISH analysis were: recurrent...
متن کاملFrequency and the Type of Chromosomal Abnormalities in Patients with Primary Amenorrhea in Northeast of Iran
متن کامل
Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?
BACKGROUND To verify whether or not microinjection of sperm with a normal nuclear shape but large vacuoles affects IVF-ICSI pregnancy outcome. METHODS A comparative study testing IVF outcome parameters of IVF-ICSI, based on morphological selection of spermatozoa with normal nuclei against those based on microinjection of sperm with a normal nuclear shape but large vacuoles. An experimental gr...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2015
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/dev202