Molecular Imaging in Pediatric Brain Tumors
نویسندگان
چکیده
منابع مشابه
Pediatric Brain Tumors: Magnetic Resonance Spectroscopic Imaging
The incidence of cancer in the United States in children under 15 years of age has risen in recent years (Ries et al., 1991). This is largely due to the increased incidence of lymphoblastic leukemia and tumors of the brain and nervous system, as opposed to Wilms tumors, soft tissue and bone sarcomas, lymphomas and Hodgkin's disease or other malignancies of childhood. Between 1973 and 1988, the ...
متن کاملMolecular mechanisms and therapeutic targets in pediatric brain tumors.
Brain tumors are among the leading causes of cancer-related deaths in children. Although surgery, aggressive radiation, and chemotherapy have improved outcomes, many patients still die of their disease. Moreover, those who survive often suffer devastating long-term side effects from the therapies. A greater understanding of the molecular underpinnings of these diseases will drive the developmen...
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Primitive neuroectodermal tumors (PNET) of the brain include medulloblastoma (MB) and central nervous system primitive neuroectodermal tumor (CNS PNET) subtypes, which share histological features yet differ at the genomic level and in clinical outcome. Delineation of the genetic anomalies between PNET subtypes is a current challenge for establishing effective targeted therapeutic strategies aga...
متن کاملImaging of common adult and pediatric primary brain tumors.
p n a he primary goals of brain tumor imaging are lesion detection, localization, delineation of extent, and characerization. This information is used to formulate an approprite differential diagnosis that is extremely helpful for the eferring neuro-surgeons and the neuro-oncologists.1,2 In adition, imaging studies play a vital role in therapy planning, uch as stereotactic location for surgery ...
متن کاملReducing excess radiation from portal imaging of pediatric brain tumors
Previously we have shown that our routine portal imaging (PI) of the craniofacial region in pediatric brain tumor patients contributed an additional 2%-3% of the prescribed dose and up to 200 cGy to the planning target volume (PTV) and nearby organs at risk (OARs). The purpose of this study is to quantify the reduction in dose to PTV and OARs from portal imaging (PI) of the craniofacial region ...
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ژورنال
عنوان ژورنال: Cancers
سال: 2019
ISSN: 2072-6694
DOI: 10.3390/cancers11121853