Molecular Imaging in Neurodegenerative Diseases

Imaging biomarkers in neurodegenerative diseases

One way to think about neurodegenerative diseases is to divide them into those that are and those that are not typically associated with dementia. For example Alzheimer’s disease (AD) is while amyotrophic lateral sclerosis or certain movement disorders are typically not associated with dementia. This talk will focus on neurodegeneration that is associated with dementia in the elderly. There are...

Strategies for molecular imaging dementia and neurodegenerative diseases

Dementia represents a heterogeneous term that has evolved to describe the behavioral syndromes associated with a variety of clinical and neuropathological changes during continuing degenerative disease of the brain. As such, there lacks a clear consensus regarding the neuropsychological and other constituent characteristics associated with various cerebrovascular changes in this disease process...

And Neurodegenerative Diseases : Molecular Aspects

FDG- PET Imaging in Neurodegenerative Brain Diseases

Increases and decreases of synaptic activity in the brain are accompanied by proportional changes in capillary perfusion and local glucose consumption. These changes in glucose consumption are the effect of changed activity or density of the afferent nerve terminals in that region. Loss of neurons may result in decreased glucose consumption in distant brain regions by deafferentiation, while al...

Exosomes: Future Perspective in Neurodegenerative Diseases

Neurodegeneration is a progressive and irreversible loss of neuronal cells in specific regions of the brain. Alzheimer Diseases (AD) Parkinson Disease (PD) are the most common forms of neurodegenerative diseases in older people. Exosomes are extracellular nanovesicles that have a key role in physiological processes such as intercellular communication, cell migration, angiogenesis, and anti-tumo...