Molecular Genetic Characterization of Thyroid Dyshormonogenesis in a French Bulldog

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Molecular Genetic Characterization of Thyroid Dyshormonogenesis in a French Bulldog

BACKGROUND A case of congenital hypothyroidism with goiter (CHG) in a juvenile French bulldog was identified and hypothesized to be caused by dyshormonogenesis of genetic etiology. OBJECTIVES To describe case management, unusual phenotypic aspects, and a CHG-causing mutation in a French bulldog. ANIMALS Thyroid tissue and blood from a CHG-affected French bulldog and 4 normal control dogs an...

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ژورنال

عنوان ژورنال: Journal of Veterinary Internal Medicine

سال: 2015

ISSN: 0891-6640,1939-1676

DOI: 10.1111/jvim.13651