Molecular Disorganization of Axons Adjacent to Human Cortical Microinfarcts
نویسندگان
چکیده
منابع مشابه
Molecular Disorganization of Axons Adjacent to Human Cortical Microinfarcts
Cortical microinfarcts (CMIs) are microscopically identified wedge-shaped ischemic lesions that occur at or near the cortical surface and result from occlusion of penetrating arterioles. These microscopic lesions can be observed with high-resolution magnetic resonance imaging in aging brains and in patients with cerebrovascular disease. Recent studies have suggested that strategically located m...
متن کاملMolecular disorganization of axons adjacent to human lacunar infarcts.
Cerebral microvascular disease predominantly affects brain white matter and deep grey matter, resulting in ischaemic damage that ranges from lacunar infarcts to white matter hyperintensities seen on magnetic resonance imaging. These lesions are common and result in both clinical stroke syndromes and accumulate over time, resulting in cognitive deficits and dementia. Magnetic resonance imaging s...
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Oda-Christina Suter, Thanomphone Sunthorn, Rudolf Kraftsik, Joel Straubel, Pushpa Darekar, Disease Cerebral Hypoperfusion Generates Cortical Watershed Microinfarcts in Alzheimer Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 1...
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Affiliations 1 Center for Applied Neuroscience, Department of Psychology, University of Cyprus, Nicosia, Cyprus 2 Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom 3 Department of Neuroscience, University of California, San Diego, San Diego CA, USA 4 Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA,...
متن کاملRelationship between cortical microinfarcts and cognitive impairment in Alzheimer's disease
Cerebrovascular disease and AD pathology co-exist in most dementia cases, and microinfarcts (MIs), particularly if cortical and multiple, play an additive and independent role in AD cognitive impairment. The main cause of cortical MIs is chronic cerebral hypoperfusion but occlusive vascular diseases, embolism and blood-brain barrier disruptions, isolated or combined, may also play a role. The p...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2017
ISSN: 1664-2295
DOI: 10.3389/fneur.2017.00405