Molecular determinants and feedback circuits regulating type 2 CRH receptor signal integration
نویسندگان
چکیده
منابع مشابه
Molecular evolution of GPCRs: CRH/CRH receptors.
Corticotrophin-releasing hormone (CRH) is the pivotal neuroendocrine peptide hormone associated with the regulation of the stress response in vertebrates. However, CRH-like peptides are also found in a number of invertebrate species. The origin of this peptide can be traced to a common ancestor of lineages leading to chordates and to arthropods, postulated to occur some 500 million years ago. E...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 2011
ISSN: 0167-4889
DOI: 10.1016/j.bbamcr.2011.02.005