Molecular concentration of kidney cortex slices

The accumulation of D-galactose against a concentration gradient by slices of rabbit kidney cortex.

The excretion of a glucose-free urine is believed to be the result of the presence, in the epithelial cells of the proximal convoluted tubules of the vertebrate kidney, of a process for the reabsorption of glucose from the glomerular filtrate against the concentration gradient (1). This belief is substantiated by analyses of the glucose concentration in samples of tubular fluid obtained by micr...

A release of renin from dog kidney cortex slices.

A release of renin from kidney cortex slices in vitro was first reported by the present authors (1). Recently, the renin release from kidney slices of rats, pretreated with de oxycorticosterone acetate, clipping of renal artery, bleeding or decapitation, was shown by Jong (2)' and BoCovic et al. (3). In their experiments, the fundamental process of renin release has not been made clear. In our ...

Divalent cation transport in kidney slices. I. Properties of calcium transport in slices of rat kidney cortex and the effects of diuretics.

Correlative studies on transports of Ca2+ and Na+ and the properties of Ca2+ transport were carried out in rat kidney cortex slices. Ouabain had no effect on the Ca2+ transport but did inhibit the Na+ transport extensively. With addition of 2,4-dinitrophenol to the incubation medium, or under the anaerobic conditions, the effluxes of Ca2+ and Na+ were inhibited while the Ca2+ influx was enhance...

The effect of potassium on intracellular bicarbonate in slices of kidney cortex.

Uptake and acetylation of p-aminohippurate by slices of mouse kidney cortex.

In slices of mouse kidney cortex, p-aminohippurate (PAH) is taken up by the organic anion transport system and then rapidly acetylated to p-acetylaminohippurate acid (PAAH), so that there is little net accumulation of PAH itself. The basic characteristics of this system have been described. Uptake may be measured as the total of PAH and PAAH combined. Both uptake and acetylation are dependent o...