Molecular characterization of the rotavirus enterotoxin NSP4 gene of strains causing diarrhoea in children aged 0-5 years in northern India
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چکیده
منابع مشابه
Molecular characterization of the rotavirus enterotoxin NSP4 gene of strains causing diarrhoea in children aged 0-5 years in northern India
Article history: Received on: 19/08/2015 Revised on: 03/09/2015 Accepted on: 30/09/2015 Available online: 27/11/2015 Non structural protein 4 (NSP4) gene of Rotavirus encodes a multifunctional protein which has significant role in viral multiplication and pathogenesis of acute watery diarrhoea associated with rotaviral gastroenteritis. It is known as the first viral enterotoxin and mutations of...
متن کاملMolecular Characterization of Rotavirus Strains Causing Gastroenteritis in Children under 5 Years in Cairo, Egypt
Globally, human rotavirus (RV) remains the most common cause of severe diarrhea in children, causing 453,000 deaths per year and proximately 2.4 million hospitalization among children aged less than 5 years, with a maximum incidence in the developing countries [1-3]. Transmissions of RVs occur mainly via fecal-oral contact but it also might be transmitted by respiratory spread [4,5]. RV group A...
متن کاملRotavirus Nonstructural Protein 4 (NSP4)-Viral Enterotoxin with Multiple roles in Pathogenesis of Diarrhoea in Children
Article history: Received on: 06/05/2015 Revised on: 24/05/2015 Accepted on: 14/07/2015 Available online: 27/07/2015 Nonstructural protein 4 (NSP4) of Rotavirus has been designated as the first viral enterotoxin. Its role in viral replication is already well known. Intensive research over the past decade has shown the involvement of this protein in many cellular activities both in ‘expressed’ a...
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A 2-year surveillance was performed in Kathmandu, Nepal, by collection of stool specimens from 1139 children aged <5 years who were hospitalized for acute diarrhea from November 2005 through October 2007. Of the 1139 samples, 379 (33%) had rotavirus strains identified by enzyme-linked immunosorbent assay; the most prevalent G type was G12, accounting for 50% of typed strains in 2005-2006 and 29...
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ژورنال
عنوان ژورنال: Journal of Applied Pharmaceutical Science
سال: 2015
ISSN: 2231-3354
DOI: 10.7324/japs.2015.501107