Molecular Characterization of Appendiceal Goblet Cell Carcinoid

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Goblet Cell Carcinoid

Goblet cell carcinoid (GCC) is a unique type of mixed endocrine-exocrine neoplasm, almost exclusively seen in the appendix. Historically, it has been variably termed as adenocarcinoid, mucinous carcinoid, microglandular carcinoma, amphicrine neoplasm, mucin-producing neuroendocrine tumor or carcinoma, and crypt cell carcinoma. GCC is the preferred term in the current literature, but this remain...

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Appendiceal Goblet Cell Carcinoid Tumour: A Case of Unexpected Lung Metastasis

Goblet cell carcinoid tumours are often considered a subset of appendiceal neuroendocrine tumours which behave more aggressively. They usually metastasize through transcoelomic/peritoneal invasion and common sites include the ovaries, peritoneum, and liver. Metastases may have goblet cell carcinoid, signet ring cell carcinoma or classic carcinoid histology. We report the first case in the liter...

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Goblet cell carcinoid of the appendix

been identified in appendiceal carcinoids: the argentaffin-positive carcinoid, the nonargentaffin carcinoid, and the mucinous, goblet cell carcinoid. Therapy for carcinoids in the first 2 classes traditionally depends on tumour size and location with respect to the base of the appendix. The third type is rarer and behaves more aggressively, hence the literature suggests that management should b...

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Goblet cell carcinoid of the appendix

Background: Goblet cell carcinoid (GCC) of the appendix is a rare neoplasm that share histological features of both adenocarcinoma and carcinoid tumor. While its malignant potential remains unclear, GCC's are more aggressive than conventional carcinoid. The clinical presentations of this neoplasm are also varied. This review summarizes the published literature on GCC of the appendix. The focus ...

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Goblet cell carcinoid tumour of the appendix.

Goblet cell carcinoid tumors (GCCT) are uncommon neoplasms that predominantly occur in the vermiform appendix. They tend to occur in middle-aged adults with a near equal sex distribution. Most Goblet cell carcinoid tumors are discovered in appendices removed for acute appendicitis and for other reasons. Goblet cell carcinoid tumors demonstrate features of both classic carcinoid tumor and adenoc...

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ژورنال

عنوان ژورنال: Molecular Cancer Therapeutics

سال: 2020

ISSN: 1535-7163,1538-8514

DOI: 10.1158/1535-7163.mct-20-0318