منابع مشابه
Comparative molecular biology of lambdoid phages.
Lambdoid phages are natural relatives of phage lambda. As a group, they are highly polymorphic in DNA sequence and biological specificity. Specificity differences have played a key role in identifying the specific sequences recognized by the N and Q antitermination proteins, the initiator O for DNA synthesis, the terminase system Nv1-A for cutting DNA during packaging, and the cI repressor prot...
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We attempted to apply a new criterion, the template specificity of RNA replicases of Escherichia coli RNA phages, for the grouping of these phages. Based on the template specificity, it was shown that (a) Qbeta, VK, and ST belonged to one group (group III), and SP and FI to another group (group IV), and (b) some similarity existed between groups III and IV. Considering such template specificity...
متن کاملMolecular characterization of three Lactobacillus delbrueckii subsp. bulgaricus phages.
In this study, three phages infecting Lactobacillus delbrueckii subsp. bulgaricus, named Ld3, Ld17, and Ld25A, were isolated from whey samples obtained from various industrial fermentations. These phages were further characterized in a multifaceted approach: (i) biological and physical characterization through host range analysis and electron microscopy; (ii) genetic assessment through genome a...
متن کاملSmall RNA biology is systems biology.
During the last decade small regulatory RNA (srRNA) emerged as central players in the regulation of gene expression in all kingdoms of life. Multiple pathways for srRNA biogenesis and diverse mechanisms of gene regulation may indicate that srRNA regulation evolved independently multiple times. However, small RNA pathways share numerous properties, including the ability of a single srRNA to regu...
متن کاملSystems biology versus molecular biology
Systems biology and molecular biology can answer the same question in quite different ways, and frequently the answers given by one sub-discipline seem no answer at all to the other. For many molecular biologists, a systemslevel explanation leaves them feeling that, until the underlying molecular mechanisms are known, the approach is hopelessly superficial. For systems biologists, on the other ...
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ژورنال
عنوان ژورنال: Nature
سال: 1976
ISSN: 0028-0836,1476-4687
DOI: 10.1038/260214a0