Molecular biological features of male germ cell differentiation
نویسندگان
چکیده
منابع مشابه
Autoradiographic evidence of human male germ-cell differentiation in vitro.
In vivo spermatogenesis of man has been thoroughly investigated recently by Heller and Clermont (1964). On the other hand, in vitro cultures of mammalian germ-cells have remained rather insufficient up to now, and the techniques currently available can hardly be used by those who are interested in genetic and endocrinologic problems of the testis. Under such a situation, efforts for successful ...
متن کاملSignaling events during male germ cell differentiation: bases and perspectives.
In all species, reproductive function depends on the ability of the individual to produce functional differentiated gametes. Spermatogenesis is a cyclic process in which diploid spermatogonia differentiate into mature haploid spermatozoa. Thus from a genetic point of view, spermatogenesis can be divided into two phases, namely the diploid and haploid phase. Indeed, this complex differentiation ...
متن کاملModeling germ cell differentiation
1. Germline differentiation of embryonic stem cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.1. Early germline fate commitment and PGC development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.2. In vitro germ cell differentiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
متن کاملMale germ cell gene expression.
Formation of the male gamete occurs in sequential mitotic, meiotic, and postmeiotic phases. Many germ cell-specific transcripts are produced during this process. Their expression is developmentally regulated and stage specific. Some of these transcripts are product of genes that are male germ cell-specific homologs of genes expressed in somatic cells, while some are expressed from unique genes ...
متن کاملThe effect of BMP4 on mouse embryonic stem cell proliferation and differentiation into primordial germ cells
Background and Aim: Artificial gamete production from stem cells is a novel strategy for treatment of infertility. Among various stem cell sources, embryonic stem cells (ESC) can be considered as an appropriate source for in vitro formation of germ cells. In this study we evaluated the effect of BMP4 on proliferation and differentiation of mouse embryonic stem cells into primordial germ cells (...
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ژورنال
عنوان ژورنال: Reproductive Medicine and Biology
سال: 2007
ISSN: 1445-5781
DOI: 10.1111/j.1447-0578.2007.00158.x