Molecular and Genetic Basis of Non-Syndromic Tooth Agenesis
نویسندگان
چکیده
منابع مشابه
Genetic basis of non-syndromic anomalies of human tooth number.
Teeth organogenesis develops through a well-ordered series of inductive events involving genes and BMP, FGF, SHH and WNT represent the main signalling pathways that regulate epithelial-mesenchymal interactions. Moreover, progress in genetics and molecular biology indicates that more than 300 genes are involved in different phases of teeth development. Mutations in genes involved in odontogenesi...
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Non-syndromic tooth agenesis (or non-syndromic congenitally missing tooth) is one of the most common congenital defects in humans affecting the craniofacial function and appearance. Single nucleotide polymorphisms (SNPs) have been associated with an individual's susceptibility to these anomalies. The aim of the present study was therefore to investigate the roles of the potentially functional S...
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Congenital Tooth Agenesis or Hypodontia is one of the most common developmental anomaly of the human dentition, presents itself with one or more missing teeth. It is a polygenetic disorder that can occur either in isolation or as a co-finding in many syndromes. The Clinical features, diagnostic characteristics and management strategies all depend on the severity of the condition, presence or ab...
متن کاملAssociation between rs11001553 of DKK1 and non-syndromic tooth agenesis in the Chinese Han population.
Tooth agenesis is one of the most common anomalies of human dentition. Recent genetic studies have provided information regarding a number of genes related to both syndromic and non-syndromic forms of hypodontia. In a previous study, we found that polymorphism in rs11001553 of DKK1 was associated with hypodontia in the Chinese Han population. In this study, we extended this investigation to 89 ...
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Background: Sexual reproduction affords the stands for conserving genetic characteristics and sequentially, genetic inconsistency may influence the capability to imitate. Materials and Methods: Research was conducted by subject in PubMed and other databases. Results: A significant number of genotypes have been related with infertility phenotypes and evaluation of precise genes in humans and mod...
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ژورنال
عنوان ژورنال: Česká stomatologie/Praktické zubní lékařství
سال: 2015
ISSN: 1213-0613,1805-4471
DOI: 10.51479/cspzl.2015.002